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CA8 Protein (His tag)

CA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 94 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7194579
  • Target See all CA8 Proteins
    CA8 (Carbonic Anhydrase VIII (CA8))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 6
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CA8 protein is labelled with His tag.
    Purpose
    Recombinant Human Carbonic Anhydrase 8/CA8 Protein (His Tag)(Active)
    Sequence
    Met 1-Gln 290
    Characteristics
    A DNA sequence encoding the human CA8 (NP_004047.3) (Met 1-Gln 290) was expressed, with a polyhistidine tag at the C-terminus.
    Purity
    > 94 % as determined by reducing SDS-PAGE.
    Biological Activity Comment
    Measured by its esterase activity. The specific activity is >100 pmoles/min/μg.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, 15 % glycerol, pH 7.5
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CA8 (Carbonic Anhydrase VIII (CA8))
    Alternative Name
    Carbonic Anhydrase 8/CA8 (CA8 Products)
    Synonyms
    AW546993 Protein, Ca8 Protein, Cals Protein, Cals1 Protein, Carp Protein, wdl Protein, zgc:110118 Protein, CA-VIII Protein, CALS Protein, CAMRQ3 Protein, CARP Protein, carbonic anhydrase 8 Protein, carbonic anhydrase VIII Protein, CAH8 Protein, Car8 Protein, ca8 Protein, CA8 Protein
    Background

    Background: The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78 % of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.

    Synonym: Carbonic Anhydrase-Related Protein, CARP, Carbonic Anhydrase VIII, CA-VIII, CA8, CALS,CAMRQ3,MGC120502,MGC99509

    Molecular Weight
    33.8 kDa
    NCBI Accession
    NP_004047
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