CHI3L2 Protein (His tag)
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- Target See all CHI3L2 Proteins
- CHI3L2 (Chitinase 3-Like 2 (CHI3L2))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CHI3L2 protein is labelled with His tag.
- Purpose
- Recombinant Human CHI3L2/YKL-39 Protein (His Tag)
- Sequence
- Tyr27-Leu390
- Characteristics
- Recombinant Human Chitinase 3-Like Protein 2 is produced by our Mammalian expression system and the target gene encoding Tyr27-Leu390 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CHI3L2 Protein
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Chitinase 3-Like 2 (CHI3L2) (AA 1-390) protein (GST tag)
CHI3L2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chitinase 3-Like 2 (CHI3L2) (AA 27-390) protein (His-SUMO Tag)CHI3L2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Chitinase 3-Like 2 (CHI3L2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)CHI3L2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Chitinase 3-Like 2 (CHI3L2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CHI3L2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Chitinase 3-Like 2 (CHI3L2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CHI3L2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CHI3L2 (Chitinase 3-Like 2 (CHI3L2))
- Alternative Name
- CHI3L2/YKL-39 (CHI3L2 Products)
- Synonyms
- CHIL2 Protein, YKL-39 Protein, YKL39 Protein, chitinase 3 like 2 Protein, CHI3L2 Protein
- Background
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Background: Chitinase 3-Like Protein 2 (CHI3L2) is a 39 kDa secreted glycoprotein which belongs to the glycosyl hydrolase 18 family and the most closely related to human cartilage glycoprotein 39, which promotes the growth of human synovial cells as well as skin and fetal lung fibroblasts. Highest expression of CHI3L2 is in chondrocytes, followed by synoviocytes, lung and heart. It is not detected in spleen, pancreas, and liver. CHI3L2 may also be expressed in developing brain and placenta. Increased levels of CHI3L2 have been demonstrated in synovial fluids of patients with rheumatoid or osteoarthritis as well as in some other pathologies and in malignant tumors, particularly in glioblastomas. CHI3L2 may bind glycan structure with high affinity, but not heparin. It has has no chitotriosidase activity, but is likely to bind some type of glycan.
Synonym: Chitinase-3-Like Protein 2, Chondrocyte Protein 39, YKL-39, CHI3L2,CHIL2,YKL-39,YKL39
- Molecular Weight
- 41.94 kDa
- UniProt
- Q15782
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