CLIC2 Protein (His tag)
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- Target See all CLIC2 Proteins
- CLIC2 (Chloride Intracellular Channel 2 (CLIC2))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CLIC2 protein is labelled with His tag.
- Purpose
- Recombinant Human CLIC2 Protein (His Tag)
- Sequence
- Met 1-Ser247
- Characteristics
- Recombinant Human Chloride Intracellular Channel Protein 2 is produced by our E.coli expression system and the target gene encoding Met1-Ser247 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CLIC2 Protein
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Chloride Intracellular Channel 2 (CLIC2) (AA 1-247) protein (His tag)
CLIC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chloride Intracellular Channel 2 (CLIC2) (AA 1-247) protein (GST tag)CLIC2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chloride Intracellular Channel 2 (CLIC2) (AA 1-247) protein (Strep Tag)Crystallography grade CLIC2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chloride Intracellular Channel 2 (CLIC2) protein (Myc-DYKDDDDK Tag)CLIC2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 20 % Glycerol, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- CLIC2 (Chloride Intracellular Channel 2 (CLIC2))
- Alternative Name
- CLIC2 (CLIC2 Products)
- Synonyms
- zgc:92762 Protein, CLIC2 Protein, CLIC2b Protein, MRXS32 Protein, XAP121 Protein, chloride intracellular channel 2 Protein, clic2 Protein, CLIC2 Protein, Clic2 Protein
- Background
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Background: Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells, it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH . CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be detected in the adult brain, liver, lung, heart, stomach, spleen and testis. It is expressed in fetal liver and adult skeletal muscle. CLIC2 is a potential candidate for one of many diseases linked to Xq28.
Synonym: Chloride Intracellular Channel Protein 2, XAP121, CLIC2
- Molecular Weight
- 30.5 kDa
- UniProt
- O15247
- Pathways
- Negative Regulation of Transporter Activity
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