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CLIC4 Protein (His tag)

CLIC4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319285
  • Target See all CLIC4 Proteins
    CLIC4 (Chloride Intracellular Channel 4 (CLIC4))
    Protein Type
    Recombinant
    Origin
    • 6
    • 3
    • 2
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CLIC4 protein is labelled with His tag.
    Purpose
    Recombinant Human CLIC4 Protein (His Tag)
    Sequence
    Met 1-Lys253
    Characteristics
    Recombinant Human Chloride Intracellular Channel Protein 4 is produced by our E.coli expression system and the target gene encoding Met1-Lys253 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CLIC4 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    CLIC4 (Chloride Intracellular Channel 4 (CLIC4))
    Alternative Name
    CLIC4 (CLIC4 Products)
    Synonyms
    CLIC4L Protein, H1 Protein, MTCLIC Protein, huH1 Protein, p64H1 Protein, cb142 Protein, wu:fb33c05 Protein, wu:fc30h10 Protein, clic4 Protein, MGC89006 Protein, CLIC4 Protein, DKFZp459A0325 Protein, D0Jmb3 Protein, TU-74 Protein, mc3s5 Protein, mtCLIC Protein, xclic4 Protein, chloride intracellular channel 4 Protein, chloride intracellular channel 4 (mitochondrial) Protein, chloride intracellular channel 4 S homeolog Protein, CLIC4 Protein, Clic4 Protein, clic4 Protein, clic4.S Protein
    Background

    Background: Chloride Intracellular Channel Protein 4 (CLIC4) is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 is expressed in various tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). CLIC4 acts as a monomer which is able to form selective ion channels in target proteins, thus facilitating the transport of chloride and other ions. CLIC4 is believed to have a role in apoptosis and is able to translocate to the nucleus under stress conditions. CLIC4 has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.

    Synonym: CLIC4L,H1,huH1,MTCLIC,p64H1

    Molecular Weight
    30.9 kDa
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