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CHRNB3 Protein (His tag)

CHRNB3 Origin: Human Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318819
  • Target See all CHRNB3 Proteins
    CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    Human
    Source
    • 5
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This CHRNB3 protein is labelled with His tag.
    Purpose
    Recombinant Human CHRNB3 Protein (His Tag)
    Sequence
    Ile25-Leu232
    Characteristics
    Recombinant Human Neuronal acetylcholine receptor subunit beta-3 is produced by our Mammalian expression system and the target gene encoding Ile25-Leu232 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
    Alternative Name
    CHRNB3 (CHRNB3 Products)
    Synonyms
    5730417K16Rik Protein, Acrb3 Protein, NACHR Protein, CHRNB3 Protein, chrnb3 Protein, cholinergic receptor nicotinic beta 3 subunit Protein, neuronal acetylcholine receptor subunit beta-3 Protein, cholinergic receptor, nicotinic, beta polypeptide 3 Protein, cholinergic receptor, nicotinic beta 3 L homeolog Protein, cholinergic receptor, nicotinic beta 3 Protein, cholinergic receptor, nicotinic, beta 3b (neuronal) Protein, cholinergic receptor, nicotinic, beta polypeptide 3a Protein, CHRNB3 Protein, CpipJ_CPIJ012638 Protein, Chrnb3 Protein, chrnb3.L Protein, chrnb3 Protein, chrnb3b Protein, chrnb3a Protein
    Background

    Background: Neuronal acetylcholine receptor subunit beta-3(CHRNB3) is a cell membrane protein and belongs to the ligand-gated ion channel (TC 1.A.9) family. CHRNB3 seems to be composed of two different type of subunits: alpha and beta. The CHRNB3 are (hetero) pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of CHRNB3 are encoded by separate genes and have different primary structure. There are several subtypes of neuronal CHRNB3 that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if like muscle alpha-1, they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits.

    Synonym: Neuronal acetylcholine receptor subunit beta-3

    Molecular Weight
    25.3 kDa
    UniProt
    Q05901
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