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CSAG1 Protein (Fc Tag)

CSAG1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317480
  • Target See all CSAG1 Proteins
    CSAG1 (Chondrosarcoma Associated Gene 1 (CSAG1))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CSAG1 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human CSAGE/CSAG1 Protein (Fc Tag)
    Sequence
    Asp20-Pro78
    Characteristics
    A DNA sequence encoding the human CSAG1 (AAH59947.1) (Asp20-Pro78) was fused with the Fc region of human IgG1 at the N-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
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    Discover our top product CSAG1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CSAG1 (Chondrosarcoma Associated Gene 1 (CSAG1))
    Alternative Name
    CSAGE/CSAG1 (CSAG1 Products)
    Synonyms
    CSAGE Protein, CT24.1 Protein, chondrosarcoma associated gene 1 Protein, CSAG1 Protein
    Background

    Background: SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

    Synonym: CSAGE,CT24.1

    Molecular Weight
    35.2 kDa
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