C12orf53 Protein (Fc Tag)
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- Target See all C12orf53 Proteins
- C12orf53 (Chromosome 12 Open Reading Frame 53 (C12orf53))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This C12orf53 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human C12orf53 Protein (Fc Tag)
- Sequence
- Met 1-Pro178
- Characteristics
- A DNA sequence encoding the human C12orf53 (Q8IYJ0-1) (Met1-Pro178) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 96 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product C12orf53 Protein
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Chromosome 12 Open Reading Frame 53 (C12orf53) (AA 32-178) protein (His tag)
Crystallography grade C12orf53 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Chromosome 12 Open Reading Frame 53 (C12orf53) (AA 28-174) protein (His tag)Crystallography grade C12orf53 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Chromosome 12 Open Reading Frame 53 (C12orf53) (AA 32-282) protein (rho-1D4 tag)Crystallography grade C12orf53 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Chromosome 12 Open Reading Frame 53 (C12orf53) (AA 28-278) protein (rho-1D4 tag)Crystallography grade C12orf53 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- C12orf53 (Chromosome 12 Open Reading Frame 53 (C12orf53))
- Alternative Name
- C12orf53 (C12orf53 Products)
- Synonyms
- C12orf53 Protein, PANP Protein, leda-1 Protein, PILR alpha associated neural protein Protein, PIANP Protein
- Background
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Background: C12orf53 is mainly expressed in adult brain and cerebellum. It also can be detected in fetal brain and virtually no expression in spleen, heart, kidney, liver and dorsal ganglion relative to brain. C12orf53 acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation. Chromosome 12 encodes over 1,100 genes within 132 million bases. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC class I interaction.
Synonym: C12orf53,leda-1,LEDA1,PANP,UNQ828/PRO1755
- Molecular Weight
- 42.3 kDa
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