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Coagulation Factor X Protein (F10) (Fc Tag)

F10 Origin: Human Host: Human Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319649
  • Target See all Coagulation Factor X (F10) Proteins
    Coagulation Factor X (F10)
    Protein Type
    Recombinant
    Origin
    • 9
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Coagulation Factor X protein is labelled with Fc Tag.
    Purpose
    Recombinant Human Coagulation Factor X/F10 Protein (Fc Tag)
    Sequence
    Asp22-Phe96
    Characteristics
    Recombinant Human Coagulation Factor X is produced by our Mammalian expression system and the target gene encoding Asn32-Lys488 is expressed with a Fc tag at the C-terminus.
    Purity
    > 85 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product F10 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM MES,150 mM NaCl,0.2 mM CaCl2, pH 5.5.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Coagulation Factor X (F10)
    Alternative Name
    Coagulation Factor X/F10 (F10 Products)
    Synonyms
    FX Protein, FXA Protein, Cf10 Protein, fX Protein, fi12c10 Protein, wu:fi12c10 Protein, F10 Protein, f10 Protein, coagulation factor X Protein, Coagulation factor X Protein, coagulation factor 10 L homeolog Protein, F10 Protein, f10 Protein, CpipJ_CPIJ012712 Protein, CpipJ_CPIJ014863 Protein, CpipJ_CPIJ016937 Protein, CpipJ_CPIJ017791 Protein, fa10 Protein, f10.L Protein
    Background

    Background: F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1-40). Both the intrinsic and extrinsic pathways activate Factor X to Xa, which consists of light (residues 41-179) and heavy (residues 235-488) chains linked by a disulfide bond. Coagulation factor X is initially synthesized in the liver. The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds. Forms a heterodimer with SERPINA5. F10 is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

    Synonym: Coagulation factor 10,coagulation factor X,FX,FXA

    Molecular Weight
    78.2 kDa
    UniProt
    P00742
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