COL8A1 Protein (His tag)
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- Target See all COL8A1 Proteins
- COL8A1 (Collagen, Type VIII, alpha 1 (COL8A1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This COL8A1 protein is labelled with His tag.
- Purpose
- Recombinant Human COL8A1 Protein (His Tag)
- Sequence
- Gly28-Met744
- Characteristics
- Recombinant Human Collagen alpha-1(VIII) Chain is produced by our Mammalian expression system and the target gene encoding Gly28-Met744 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product COL8A1 Protein
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Collagen, Type VIII, alpha 1 (COL8A1) (AA 572-744) protein (His tag)
Crystallography grade COL8A1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Collagen, Type VIII, alpha 1 (COL8A1) (AA 573-744) protein (His tag)Crystallography grade COL8A1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Collagen, Type VIII, alpha 1 (COL8A1) (AA 28-744) protein (His tag)Crystallography grade COL8A1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Collagen, Type VIII, alpha 1 (COL8A1) (AA 25-744) protein (His tag)Crystallography grade COL8A1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- COL8A1 (Collagen, Type VIII, alpha 1 (COL8A1))
- Alternative Name
- COL8A1 (COL8A1 Products)
- Synonyms
- COL8A1 Protein, Col8a-1 Protein, C3orf7 Protein, collagen type VIII alpha 1 chain Protein, collagen, type VIII, alpha 1 S homeolog Protein, collagen, type VIII, alpha 1 Protein, COL8A1 Protein, col8a1.S Protein, Col8a1 Protein
- Background
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Background: Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement membrane of the corneal endothelium. COL8A1 forms homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrhedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 contains one C1q domain and is primarily expressed in the subendothelium of large blood vessels. The expression level can be up-regulated during vascular injury, in atherosclerosis and in diabetes. COL8A1 may have a role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
Synonym: Collagen Alpha-1(VIII) Chain, Endothelial Collagen, Vastatin, COL8A1, C3orf7
- Molecular Weight
- 71.6 kDa
- UniProt
- P27658
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