COLEC11 Protein (His tag)
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- Target See all COLEC11 Proteins
- COLEC11 (Collectin Sub-Family Member 11 (COLEC11))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This COLEC11 protein is labelled with His tag.
- Purpose
- Recombinant Human Collectin-11/COLEC11 Protein (His Tag)
- Sequence
- Gln26-Met271
- Characteristics
- Recombinant Human Collectin-11 is produced by our Mammalian expression system and the target gene encoding Gln26-Met271 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product COLEC11 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- COLEC11 (Collectin Sub-Family Member 11 (COLEC11))
- Alternative Name
- Collectin-11/COLEC11 (COLEC11 Products)
- Synonyms
- COLEC11 Protein, 3MC2 Protein, CL-K1-I Protein, CL-K1-II Protein, CL-K1-IIa Protein, CL-K1-IIb Protein, CLK1 Protein, 1010001H16Rik Protein, wu:fb82e09 Protein, zgc:103572 Protein, collectin subfamily member 11 Protein, collectin sub-family member 11 Protein, collectin subfamily member 11 L homeolog Protein, COLEC11 Protein, Colec11 Protein, colec11 Protein, colec11.L Protein
- Background
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Background: Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS). It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2).
Synonym: Collectin-11, Collectin Kidney Protein 1, CL-K1, COLEC11
- Molecular Weight
- 27.1 kDa
- UniProt
- Q9BWP8
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