C1QB Protein (His tag)
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- Target See all C1QB Proteins
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This C1QB protein is labelled with His tag.
- Purpose
- Recombinant Human C1QB/C1qB Protein (His Tag)
- Sequence
- Met 1-Ala 253
- Characteristics
- A DNA sequence encoding the human C1QB (NP_000482.3) precursor (Met 1-Ala 253) was expressed, with a carboxy-terminal polyhistidine tag.
- Purity
- > 94 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product C1QB Protein
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Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 1-253) protein (GST tag)
C1QB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 28-253) protein (His tag)Crystallography grade C1QB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 26-253) protein (His tag)Crystallography grade C1QB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Complement Component 1, Q Subcomponent, B Chain (C1QB) protein (Myc-DYKDDDDK Tag)C1QB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, 0.5 mM TCEP, 10 % glycerol, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
- Alternative Name
- C1QB/C1qB (C1QB Products)
- Synonyms
- complement C1q B chain Protein, complement component 1, q subcomponent, beta polypeptide Protein, C1QB Protein, C1qb Protein
- Background
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Background: Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Southern blot analysis of chromosomal DNA from vertebrate species demonstrated highest similarity between the C1qB genes, followed by C1qC and finally C1qA. Sequence comparison of C1q from three different species have shown that the B chains have the strongest similarity. C1q was already present at embryonic day 14 (E14) and showed little change in abundance through six weeks postnatal. At E16, C1qB mRNA was present at high abundance in putative microglia/macrophages in cortical marginal and intermediate zones, and hippocampal analge.
Synonym: C1QB
- Molecular Weight
- 25 kDa
- NCBI Accession
- NP_000482
- Pathways
- Complement System
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