CNTN3 Protein (Fc Tag)
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- Target See all CNTN3 products
- CNTN3 (Contactin 3 (Plasmacytoma Associated) (CNTN3))
- Protein Type
- Recombinant
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Origin
- Rat
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CNTN3 protein is labelled with Fc Tag.
- Purpose
- Recombinant Rat Contactin 3/CNTN3 Protein (Fc Tag)
- Sequence
- Met1-Gly1001
- Characteristics
- A DNA sequence encoding the rat CNTN3 (Met1-Gly1001) was expressed with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 85 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
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Contactin 3 (Plasmacytoma Associated) (CNTN3) protein (His tag)
CNTN3 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Contactin 3 (Plasmacytoma Associated) (CNTN3) protein (His tag)CNTN3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Contactin 3 (Plasmacytoma Associated) (CNTN3) (AA 20-1002) protein (His tag)Crystallography grade CNTN3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Contactin 3 (Plasmacytoma Associated) (CNTN3) (AA 20-1002) protein (His tag)Crystallography grade CNTN3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Contactin 3 (Plasmacytoma Associated) (CNTN3) proteinCNTN3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CNTN3 (Contactin 3 (Plasmacytoma Associated) (CNTN3))
- Alternative Name
- Contactin 3/CNTN3 (CNTN3 Products)
- Synonyms
- Pang Protein, BIG-1 Protein, PANG Protein, PCS Protein, contactin 3 Protein, CNTN3 Protein, Cntn3 Protein
- Background
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Background: Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-3, also known as CNTN3 ( BIG-1 in rat and PANG in mouse ), is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. In the brain, Contactin-3 is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Contactin-3 contains 4 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. Human Contactin-3 shares 92 % aa identity with mouse Contactin-3.The exact function of Contactin-3 is unclear. Contactin-3 may mediate cell-cell interaction and may promote neurite outgrowth.
Synonym: CNTN3
- Molecular Weight
- 134.8 kDa
- NCBI Accession
- NP_062202
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