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CKMT1A Protein (His tag)

CKMT1A Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7195282
  • Target See all CKMT1A Proteins
    CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
    Protein Type
    Recombinant
    Origin
    • 2
    • 2
    • 2
    • 2
    • 2
    Human
    Source
    • 10
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This CKMT1A protein is labelled with His tag.
    Purpose
    Recombinant Human CKMT1A Protein (His Tag)
    Sequence
    Ala 40-His 417
    Characteristics
    A DNA sequence encoding human CKMT1A (P12532-1) (Ala40-His417) was expressed, with a polyhistide tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % glycerol
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
    Alternative Name
    CKMT1A (CKMT1A Products)
    Synonyms
    CKMT1 Protein, Mt-CK Protein, ScCKmit Protein, UbCKmit Protein, mi-CK Protein, Ckmt1 Protein, CKMT1B Protein, Mia-CK Protein, U-MtCK Protein, creatine kinase, mitochondrial 1A Protein, creatine kinase U-type, mitochondrial-like Protein, creatine kinase, mitochondrial 1, ubiquitous Protein, creatine kinase U-type, mitochondrial Protein, CKMT1A Protein, LOC100228000 Protein, Ckmt1 Protein, LOC100725326 Protein
    Background

    Background: CKMT1A belongs to the ATP:guanido phosphotransferase family. It contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. CKMT1A gene is one of two genes which encode the ubiquitous mitochondrial creatine kinase (CKMT1). CKMT1 is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK, encoded by separate genes. CKMT1 occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric CKMT1.

    Synonym: CKMT,CKMT1,CKMT1A

    Molecular Weight
    45.3 kDa
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