CKMT1A Protein (His tag)
-
- Target See all CKMT1A Proteins
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CKMT1A protein is labelled with His tag.
- Purpose
- Recombinant Human CKMT1A Protein (His Tag)
- Sequence
- Ala 40-His 417
- Characteristics
- A DNA sequence encoding human CKMT1A (P12532-1) (Ala40-His417) was expressed, with a polyhistide tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
-
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % glycerol
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- Alternative Name
- CKMT1A (CKMT1A Products)
- Synonyms
- CKMT1 Protein, Mt-CK Protein, ScCKmit Protein, UbCKmit Protein, mi-CK Protein, Ckmt1 Protein, CKMT1B Protein, Mia-CK Protein, U-MtCK Protein, creatine kinase, mitochondrial 1A Protein, creatine kinase U-type, mitochondrial-like Protein, creatine kinase, mitochondrial 1, ubiquitous Protein, creatine kinase U-type, mitochondrial Protein, CKMT1A Protein, LOC100228000 Protein, Ckmt1 Protein, LOC100725326 Protein
- Background
-
Background: CKMT1A belongs to the ATP:guanido phosphotransferase family. It contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. CKMT1A gene is one of two genes which encode the ubiquitous mitochondrial creatine kinase (CKMT1). CKMT1 is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK, encoded by separate genes. CKMT1 occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric CKMT1.
Synonym: CKMT,CKMT1,CKMT1A
- Molecular Weight
- 45.3 kDa
-