CFC1 Protein (His tag)

Catalog No. ABIN7318343

Product Details

Target: CFC1 (Cripto, FRL-1, Cryptic Family 1 (CFC1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CFC1 protein is labelled with His tag.

Purpose: Recombinant Human Cryptic/CFC1 Protein (His Tag)

Sequence: Tyr26-Gly169

Characteristics: Recombinant Human Cryptic protein is produced by our Mammalian expression system and the target gene encoding Tyr26-Gly169 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CFC1 (Cripto, FRL-1, Cryptic Family 1 (CFC1))

Alternative Name: Cryptic/CFC1 (CFC1 Products)

Synonyms: CFC1B Protein, RGD1562188 Protein, Cripto-1 Protein, FRL-1 Protein, cfc1 Protein, cr1 Protein, cripto Protein, frl1 Protein, tdgf1 Protein, xcr1 Protein, CRYPTIC Protein, DTGA2 Protein, HTX2 Protein, AV265756 Protein, b2b970Clo Protein, cryptic Protein, CFC1 Protein, cryptic family protein 1B Protein, cripto, FRL-1, cryptic family 1 Protein, teratocarcinoma-derived growth factor 1, member 3 Protein, LOC459608 Protein, Cfc1 Protein, CFC1 Protein, tdgf1.3 Protein

Background:

Background: Cryptic (CFC1) is a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. It contains an EGF-like domain, and is glycosylated on its N-terminal during post-translational modification. Cryptic is identified as a NODAL coreceptor involved in the correct establishment of the left-right axis. It may play a role in mesoderm and/or neural patterning during gastrulation. The unnormal expression of this gene may causes a series of diseases such as HTX2, Transposition of the great arteries dextro-looped 2, and Conotruncal heart malformations.

Synonym: Cryptic protein,Cryptic family protein 1,CFC1

Molecular Weight: 16.9 kDa

UniProt: P0CG37