CUTC Protein (His tag)
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- Target See all CUTC Proteins
- CUTC (CutC Copper Transporter Homolog (CUTC))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CUTC protein is labelled with His tag.
- Purpose
- Recombinant Human CUTC/CGI-32 Protein (His Tag)
- Sequence
- Met 1-Val 273
- Characteristics
- A DNA sequence encoding the human CUTC (Q9NTM9) (Met 1-Val 273) was expressed, with an N-terminal polyhistidine tag.
- Purity
- > 92 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CUTC Protein
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CutC Copper Transporter Homolog (CUTC) (AA 1-273) protein (GST tag)
CUTC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
CutC Copper Transporter Homolog (CUTC) (AA 1-273) protein (Strep Tag)Crystallography grade CUTC Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
CutC Copper Transporter Homolog (CUTC) (AA 1-272) protein (Strep Tag)Crystallography grade CUTC Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
CutC Copper Transporter Homolog (CUTC) protein (Myc-DYKDDDDK Tag)CUTC Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, 10 % glycerol, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CUTC (CutC Copper Transporter Homolog (CUTC))
- Alternative Name
- CUTC/CGI-32 (CUTC Products)
- Synonyms
- zgc:103406 Protein, RP11-483F11.3 Protein, 2310039I18Rik Protein, AI326282 Protein, CGI-32 Protein, cutC copper transporter Protein, cutC copper transporter homolog (E. coli) Protein, CUTC Protein, cutc Protein, Cutc Protein
- Background
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Background: Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to the CutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+ per subunit. Copper is an essential trace element to life and particularly plays a pivotal role in the physiology of aerobic organisms. Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and eukaryotic organisms. To sustain an adequate supply of copper, a cell requires molecular mechanisms that control the metal content to avoid copper toxicity. This toxicity comes primarily from the reactivity of copper, which can lead to the generation of free radicals. In bacteria, two independent systems are responsible for maintaining the balance of copper within the cells ( Cop and Cut family proteins ). The Cut protein family is associated with copper homeostasis and involved in uptake, storage, delivery, and efflux of copper. CutC is a member of the Cut family and is suggested to be involved in efflux trafficking of cuprous ion. CutC is able to respond transcriptionally to copper and to participate in the control of copper homeostasis in E. faecalis.
Synonym: CGI-32
- Molecular Weight
- 31 kDa
- UniProt
- Q9NTM9
- Pathways
- Transition Metal Ion Homeostasis
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