CSRP1 Protein (His tag)

Catalog No. ABIN7320243

Product Details

Target: CSRP1 (Cysteine and Glycine-Rich Protein 1 (CSRP1))

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CSRP1 protein is labelled with His tag.

Purpose: Recombinant Mouse CSRP1 Protein (His Tag)

Sequence: Met 1-Glu 193

Characteristics: A DNA sequence encoding the mouse CSRP1 (P97315) (Met 1-Glu 193) was expressed, with a polyhistide tag at the C-terminus.

Purity: > 95 % as determined by SDS-PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CSRP1 (Cysteine and Glycine-Rich Protein 1 (CSRP1))

Alternative Name: CSRP1 (CSRP1 Products)

Synonyms: CRP Protein, CRP1 Protein, CSRP Protein, CYRP Protein, D1S181E Protein, AA408841 Protein, AA959891 Protein, AW545626 Protein, Csrp Protein, cb796 Protein, csrp1 Protein, zgc:77332 Protein, MGC85577 Protein, MGC89932 Protein, CSRP1 Protein, zgc:158737 Protein, cysteine and glycine rich protein 1 Protein, cysteine and glycine-rich protein 1 Protein, cysteine and glycine-rich protein 1a Protein, cysteine and glycine rich protein 1 L homeolog Protein, cysteine and glycine-rich protein 1b Protein, Cysteine and glycine-rich protein 1 Protein, CSRP1 Protein, Csrp1 Protein, csrp1a Protein, csrp1.L Protein, csrp1 Protein, csrp1b Protein, LOC100304834 Protein, Tsp_01053 Protein

Background:

Background: Cysteine and glycine-rich protein 1, also known as Cysteine-rich protein 1, CSRP1 and CSRP, is a member of the CSRP family which may be involved in regulatory processes important for development and cellular differentiation. CSRP1 contains two LIM zinc-binding domains. The LIM / double zinc-finger motif found in CSRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Zebrafish CSRP1 is expressed in the mesendoderm and its derivatives. CSRP1 interacts with Dishevelled 2 (Dvl2) and Diversin (Div), which control cell morphology and other dynamic cell behaviors via the noncanonical Wnt and JNK pathways. When CSRP1 message is knocked down, abnormal convergent extension cell movement is induced, resulting in severe deformities in midline structures. In addition, cardiac bifida is induced as a consequence of defects in cardiac mesoderm cell migration. CSRP1 acts as a key molecule of the noncanonical Wnt pathway, which orchestrates cell behaviors during dynamic morphogenetic movements of tissues and organs.

Synonym: AA408841;AA959891;AW545626;CRP1;Csrp

Molecular Weight: 22 kDa

UniProt: P97315