Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) protein (His tag)
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- Target See all Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) Proteins
- Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Recombinant Human CMPK1 Protein (His Tag)
- Sequence
- Met 1-Gly 196
- Characteristics
- A DNA sequence encoding the human CMPK1 (P30085) (Met1-Gly196) was fused with a polyhistide tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CMPK1 Protein
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Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (AA 72-181) protein (GST tag)
CMPK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (AA 1-228) protein (His tag)CMPK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (AA 1-228) protein (GST tag)CMPK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (AA 1-196) protein (Strep Tag)Crystallography grade CMPK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (AA 1-196) protein (Strep Tag)Crystallography grade CMPK1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CMPK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 20 mM Tris, 500 mM Nacl, pH 7.4, 10 % glycerol
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
- Alternative Name
- CMPK1 (CMPK1 Products)
- Synonyms
- CK Protein, CMK Protein, CMPK Protein, UMK Protein, UMP-CMPK Protein, UMPK Protein, UMP/CMPK Protein, PSPTO1749 Protein, cmpk1 Protein, fb52d08 Protein, fk47a07 Protein, ump Protein, wu:fb52d08 Protein, wu:fk47a07 Protein, zgc:56452 Protein, Cmpk Protein, RGD1310116 Protein, cmpk Protein, 0610011D08Rik Protein, UMP-CMPk Protein, UCK Protein, cytidine/uridine monophosphate kinase 1 Protein, cytidylate kinase Protein, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic Protein, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic S homeolog Protein, cytidylate kinase Cmk Protein, cytidine monophosphate (UMP-CMP) kinase 1 Protein, CMPK1 Protein, cmk Protein, cmpk1 Protein, cmpk Protein, Cmpk1 Protein, cmpk1.S Protein, Mrub_0478 Protein, MMAH_RS06670 Protein, TAGG_RS04320 Protein, Trad_0784 Protein, Deba_2713 Protein, Toce_1154 Protein, VDIS_RS03585 Protein, Fbal_1939 Protein, Ilyop_1379 Protein, Lbys_3481 Protein, Calni_0093 Protein, Ftrac_1556 Protein, Ocepr_1777 Protein
- Background
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Background: CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.
Synonym: CK,CMK,CMPK,UMK,UMP-CMPK,UMPK
- Molecular Weight
- 24.5 kDa
- UniProt
- P30085
- Pathways
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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