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CYB5R1 Protein (His tag)

CYB5R1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317282
  • Target See all CYB5R1 Proteins
    CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CYB5R1 protein is labelled with His tag.
    Purpose
    Recombinant Human CYB5R1 Protein (His Tag)
    Sequence
    Leu 29-Tyr 305
    Characteristics
    A DNA sequence encoding the human CYB5R1 (Q9UHQ9) (Leu 29-Tyr 305) was expressed, with a polyhistidine tag at the N-terminus.
    Purity
    > 97 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CYB5R1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
    Alternative Name
    CYB5R1 (CYB5R1 Products)
    Synonyms
    B5R.1 Protein, B5R1 Protein, B5R2 Protein, NQO3A2 Protein, humb5R2 Protein, 1500005G05Rik Protein, C80155 Protein, Nqo3a2 Protein, NAD(P)H:quinone oxidoreductase type 3, polypeptide A2 Protein, cytochrome b5 reductase 1 Protein, CYB5R1 Protein, Cyb5r1 Protein
    Background

    Background: Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis, TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.

    Synonym: B5R.1,B5R1,B5R2,humb5R2,NQO3A2,PRO9865,UNQ3049

    Molecular Weight
    33.5 kDa
    UniProt
    Q9UHQ9
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