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DTYMK Protein (His tag)

DTYMK Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319085
  • Target See all DTYMK Proteins
    DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))
    Protein Type
    Recombinant
    Origin
    • 7
    • 2
    • 1
    • 1
    Human
    Source
    • 6
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This DTYMK protein is labelled with His tag.
    Purpose
    Recombinant Human Thymidylate Kinase/DTYMK Protein (His Tag)
    Sequence
    Met 1-Lys212
    Characteristics
    Recombinant Human Thymidylate kinase is produced by our Mammalian expression system and the target gene encoding Met1-Lys212 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DTYMK Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))
    Alternative Name
    Thymidylate Kinase/DTYMK (DTYMK Products)
    Synonyms
    tymk Protein, wu:fa12c02 Protein, wu:fb14h07 Protein, wu:ft84f02 Protein, zgc:123174 Protein, DTYMK Protein, MGC81047 Protein, Tb08.28L1.680 Protein, Tb08.10J17.310 Protein, DDBDRAFT_0188698 Protein, DDBDRAFT_0230101 Protein, DDB_0188698 Protein, DDB_0230101 Protein, AU044245 Protein, CDC8 Protein, D10Ertd203e Protein, TMPK Protein, TYPK Protein, Tmk Protein, mtmk Protein, PP3731 Protein, TYMK Protein, deoxythymidylate kinase Protein, deoxythymidylate kinase (thymidylate kinase) Protein, deoxythymidylate kinase S homeolog Protein, thymidylate kinase Protein, dTMP kinase Protein, Dtymk Protein, dtymk Protein, DTYMK Protein, dtymk.S Protein, Tmk Protein, CNC04630 Protein, Tb927.8.3510 Protein, Tb927.8.3910 Protein, Ndas_4954 Protein, Mesil_2461 Protein, Slip_0046 Protein, Trad_0568 Protein, Olsu_1446 Protein, Acear_0042 Protein, Igag_1070 Protein, LOC100195817 Protein
    Background

    Background: Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest that the cDNA codes for authentic human dTMP kinase. The mRNA levels and enzyme activities corresponded to cell cycle progression and cell growth stages.

    Synonym: Thymidylate kinase,dTMP kinase,DTYMK,CDC8, TMPK, TYMK

    Molecular Weight
    24.9 kDa
    UniProt
    P23919
    Pathways
    Nucleotide Phosphorylation
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