EPH Receptor A3 Protein (EPHA3) (Fc Tag)
Quick Overview for EPH Receptor A3 Protein (EPHA3) (Fc Tag) (ABIN7195520)
Target
See all EPH Receptor A3 (EPHA3) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purification tag / Conjugate
- This EPH Receptor A3 protein is labelled with Fc Tag.
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Purpose
- Recombinant Rat EphA3 Protein (Fc Tag)(Active)
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Sequence
- Met1-His541
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Characteristics
- A DNA sequence encoding the rat EPHA3 (EDL75897.1) (Met1-His541) was expressed with the Fc region of human IgG1 at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
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Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized ratEFNA5-His at 10 μg/ml (100 μl/well) can bind rat EPHA3-Fc, The EC50 of rat EPHA3-Fc is 12.1-28.4 ng/ml.
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EPH Receptor A3 (EPHA3) (AA 21-541) protein (His tag,mFc Tag)
EPHA3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
EPH Receptor A3 (EPHA3) (AA 21-541) (Active) protein (His tag)EPHA3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
EPH Receptor A3 (EPHA3) (AA 1-514) (Active) protein (His tag)EPHA3 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
EPH Receptor A3 (EPHA3) (AA 21-541) (Active) protein (His tag)EPHA3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
EPH Receptor A3 (EPHA3) (Active) protein (His tag)EPHA3 Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
EPH Receptor A3 (EPHA3) (Active) protein (His tag)EPHA3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
EPH Receptor A3 (EPHA3) (AA 569-984) protein (GST tag,His tag)EPHA3 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
EPH Receptor A3 (EPHA3) (Active) protein (Fc Tag)EPHA3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
EPH Receptor A3 (EPHA3) (AA 1-983) protein (GST tag)EPHA3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- EPH Receptor A3 (EPHA3)
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Alternative Name
- EphA3
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Background
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Background: EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: EPHA3
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Molecular Weight
- 85.8 kDa
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Pathways
- RTK Signaling, Regulation of Cell Size
Target
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