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Ephrin A5 Protein (EFNA5) (Fc Tag)

EFNA5 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318439
  • Target See all Ephrin A5 (EFNA5) Proteins
    Ephrin A5 (EFNA5)
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Ephrin A5 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human Ephrin-A5/EFNA5 Protein (Fc Tag)
    Sequence
    Gln21-Asn203
    Characteristics
    Recombinant Human Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Asn203 is expressed with a Fc tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product EFNA5 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Ephrin A5 (EFNA5)
    Alternative Name
    Ephrin-A5/EFNA5 (EFNA5 Products)
    Synonyms
    EFNA5 Protein, af1 Protein, efl5 Protein, rags Protein, eplg7 Protein, lerk7 Protein, AL-1 Protein, AV158822 Protein, EFL-5 Protein, Ephrin-A5 Protein, Epl7 Protein, LERK-7 Protein, RAGS Protein, Lerk7 Protein, AF1 Protein, EFL5 Protein, EPLG7 Protein, GLC1M Protein, LERK7 Protein, ephrin A5 Protein, EFNA5 Protein, efna5 Protein, Efna5 Protein
    Background

    Background: Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.

    Synonym: Ephrin-A5,EPLG7, LERK7,EFNA5,LERK-7,EPH-related receptor tyrosine kinase ligand 7,AL-1

    Molecular Weight
    48.3 kDa
    UniProt
    P52803
    Pathways
    RTK Signaling
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