Ephrin A5 Protein (EFNA5) (His tag)
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- Target See all Ephrin A5 (EFNA5) Proteins
- Ephrin A5 (EFNA5)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This Ephrin A5 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Ephrin-A5/EFNA5 Protein (His Tag)(Active)
- Sequence
- Gln21-Gln206
- Characteristics
- Recombinant Mouse Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Gln206 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human EphA8-Fc(Cat: PKSH032386) at 1.5μg/ml(100 μl/well) can bind Human EFNA5-His. The ED50 of EFNA5-His is 12.63ug/ml .
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Ephrin A5 (EFNA5) (AA 114-203) protein (GST tag)
EFNA5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ephrin A5 (EFNA5) (AA 21-203), (full length) protein (His tag)EFNA5 Origin: Rat Host: Yeast Recombinant > 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Ephrin A5 (EFNA5)
- Alternative Name
- Ephrin-A5/EFNA5 (EFNA5 Products)
- Synonyms
- EFNA5 Protein, af1 Protein, efl5 Protein, rags Protein, eplg7 Protein, lerk7 Protein, AL-1 Protein, AV158822 Protein, EFL-5 Protein, Ephrin-A5 Protein, Epl7 Protein, LERK-7 Protein, RAGS Protein, Lerk7 Protein, AF1 Protein, EFL5 Protein, EPLG7 Protein, GLC1M Protein, LERK7 Protein, ephrin A5 Protein, EFNA5 Protein, efna5 Protein, Efna5 Protein
- Background
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Background: Ephrin-A5 is a glycosylphosphatidylinositol (GPI)-anchored protein of the ephrin-A subclass of ephrin ligands that binds to the EphA subclass of Eph receptors. Ephrin-A5 has also been shown to bind to the EphB2 receptor. It is crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-A5 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
Synonym: Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, Epl7, Eplg7, Lerk7, Efna5,
- Molecular Weight
- 22.5 kDa
- UniProt
- O08543
- Pathways
- RTK Signaling
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