ERO1L Protein (His tag)
-
- Target See all ERO1L Proteins
- ERO1L (ERO1-Like Protein alpha (ERO1L))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This ERO1L protein is labelled with His tag.
- Purpose
- Recombinant Human ERO1A/ERO1L Protein (His Tag)
- Sequence
- Glu24-His468
- Characteristics
- Recombinant Human ERO1-Like Protein alpha is produced by our Mammalian expression system and the target gene encoding Glu24-His468 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ERO1L Protein
-
ERO1-Like Protein alpha (ERO1L) (AA 24-468) protein (His tag)
ERO1L Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
ERO1-Like Protein alpha (ERO1L) (AA 1-468) protein (GST tag)ERO1L Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
ERO1-Like Protein alpha (ERO1L) (AA 90-178) protein (GST tag)ERO1L Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
ERO1-Like Protein alpha (ERO1L) (AA 24-468) protein (His tag)Crystallography grade ERO1L Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
ERO1-Like Protein alpha (ERO1L) (AA 24-464) protein (His tag)Crystallography grade ERO1L Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
ERO1-Like Protein alpha (ERO1L) protein (Myc-DYKDDDDK Tag)ERO1L Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- ERO1L (ERO1-Like Protein alpha (ERO1L))
- Alternative Name
- ERO1A/ERO1L (ERO1L Products)
- Synonyms
- ERO1-L Protein, ero1-alpha Protein, ero1lb Protein, ERO1L Protein, ero1l Protein, ERO1-alpha Protein, ERO1A Protein, zgc:63959 Protein, endoplasmic reticulum oxidoreductase alpha L homeolog Protein, endoplasmic reticulum oxidoreductase 1 alpha Protein, endoplasmic reticulum oxidoreductase alpha Protein, ERO1-like (S. cerevisiae) Protein, ero1a.L Protein, ERO1A Protein, ero1a Protein, Ero1l Protein, Ero1a Protein
- Background
-
Background: ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. ERO1L acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. It associates with ERP44, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. ERO1L may be responsible for a significant proportion of reactive oxygen species (ROS) in the cell. ERO1L responses to temperature stimulus, protein thiol-disulfide exchange, protein folding with or without chaperone cofactor and transport.
Synonym: ERO1-Like Protein Alpha, ERO1-L, ERO1-L-Alpha, Endoplasmic Oxidoreductin-1-Like Protein, Oxidoreductin-1-L-Alpha, ERO1L
- Molecular Weight
- 53.0 kDa
- UniProt
- Q96HE7
- Pathways
- Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation
-
