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FAM171B Protein (His tag)

FAM171B Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7195640
  • Target See all FAM171B Proteins
    FAM171B (Family with Sequence Similarity 171, Member B (FAM171B))
    Protein Type
    Recombinant
    Origin
    • 4
    • 3
    Human
    Source
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FAM171B protein is labelled with His tag.
    Purpose
    Recombinant Human FAM171B/KIAA1946 Protein (His Tag)
    Sequence
    Met 1-Thr355
    Characteristics
    A DNA sequence encoding the human FAM171B (AAH60872.1) (Met1-Thr355) was expressed with a C-terminal polyhistidine tag.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product FAM171B Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    FAM171B (Family with Sequence Similarity 171, Member B (FAM171B))
    Alternative Name
    FAM171B/KIAA1946 (FAM171B Products)
    Synonyms
    KIAA1946 Protein, D430039N05Rik Protein, family with sequence similarity 171 member B Protein, family with sequence similarity 171, member B Protein, FAM171B Protein, Fam171b Protein
    Background

    Background: RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution, high concentrations are found in the brain, lung, liver, heart and spleen with lower expression levels present in the testes, gastrointestinal tract and thyroid. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. They are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of RAMP3 protein, CRLR functions as an adrenomedullin receptor.

    Synonym: KIAA1946

    Molecular Weight
    37.5 kDa
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