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FAM19A4 Protein (His tag)

FAM19A4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318954
  • Target See all FAM19A4 Proteins
    FAM19A4 (Family with Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A4 (FAM19A4))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This FAM19A4 protein is labelled with His tag.
    Purpose
    Recombinant Human FAM19A4 Protein (His Tag)
    Sequence
    Ser35-Arg140
    Characteristics
    Recombinant Human Family with Sequence Similarity 19, Member A4 is produced by our E.coli expression system and the target gene encoding Ser35-Arg140 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product FAM19A4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    FAM19A4 (Family with Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A4 (FAM19A4))
    Alternative Name
    FAM19A4 (FAM19A4 Products)
    Synonyms
    TAFA-4 Protein, TAFA4 Protein, C130034I18Rik Protein, Fam19a4 Tafa-4 Protein, Tafa-4 Protein, family with sequence similarity 19 member A4, C-C motif chemokine like Protein, family with sequence similarity 19, member A4 Protein, FAM19A4 Protein, Fam19a4 Protein
    Background

    Background: FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine residues. The FAM19A4 proteins are predominantly expressed in specific regions of the brain and the biological functions of FAM19A4 family members remain to be determined, but there are a few tentative hypotheses. First, FAM19A4 may modulate immune responses in the CNS by functioning as brain specific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. Second, FAM19A4 may represent a novel class of neurokines that act as regulators of immune nervous cells. And third, FAM19A4 may control axonal sprouting following brain injury.

    Synonym: Protein FAM19A4,Chemokine-like protein TAFA-4,TAFA4,family with sequence similarity 19 (chemokine (C-C motif)-like), member A4, FAM19A4, chemokine-like protein TAFA-4

    Molecular Weight
    14.1 kDa
    UniProt
    Q96LR4
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