FETUB Protein (His tag)
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- Target See all FETUB Proteins
- FETUB (Fetuin B (FETUB))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This FETUB protein is labelled with His tag.
- Purpose
- Recombinant Human Fetuin-B/FETUB Protein (His Tag)
- Sequence
- Cys16-Pro382
- Characteristics
- Recombinant Human Fetuin B is produced by our Mammalian expression system and the target gene encoding Cys16-Pro382 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product FETUB Protein
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Fetuin B (FETUB) (AA 177-382) protein (His-IF2DI Tag)
FETUB Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Fetuin B (FETUB) (AA 1-382) protein (GST tag)FETUB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fetuin B (FETUB) protein (His tag)FETUB Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Fetuin B (FETUB) (AA 16-382) protein (His tag)Crystallography grade FETUB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Fetuin B (FETUB) (AA 19-388) protein (His tag)Crystallography grade FETUB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- FETUB (Fetuin B (FETUB))
- Alternative Name
- Fetuin-B/FETUB (FETUB Products)
- Synonyms
- 16G2 Protein, Gugu Protein, IRL685 Protein, Fet Protein, Pp63 Protein, gugu Protein, fetuin-b Protein, FETUB Protein, 16g2 Protein, irl685 Protein, im:6910148 Protein, 2310011O17Rik Protein, AI255764 Protein, D17980 Protein, fetuin B Protein, fetuin B L homeolog Protein, fetuin beta Protein, FETUB Protein, Fetub Protein, fetub.L Protein, fetub Protein
- Background
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Background: Fetuin-B is a member of the Fetuin family that is part of the Cystatin superfamily of Cysteine Protease inhibitors. It is reported that Fetuin-B is highly expressed in liver tissue, in tongue and placenta tissues. Fetuin-B is a paralogue of Fetuin-A. Fetuin-A and Fetuin-B display similarities and differences in their characteristics, however, they share only 20 % amino acid sequence identity. The amounts of Fetuin-B in human serum, unlike Fetuin-A, vary with gender and are higher in females than in males. Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than Fetuin-A. Fetuin-B expression is decreased in Fetuin-A deficient knock-out mice. The expression of Fetuin-B has been shown to be regulated by FXR (Farnesoid X Receptor), a nuclear receptor activated by bile acids. Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice. The function of Fetuin B is still not fully characterized.
Synonym: Fetuin-B, 16G2, Fetuin-Like Protein IRL685, Gugu, FETUB
- Molecular Weight
- 41.5 kDa
- UniProt
- Q9UGM5
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