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FKBP4 Protein (His tag)

FKBP4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318885
  • Target See all FKBP4 Proteins
    FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
    Protein Type
    Recombinant
    Origin
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This FKBP4 protein is labelled with His tag.
    Purpose
    Recombinant Human FKBP4 Protein (His Tag)
    Sequence
    Met 1-Ala459
    Characteristics
    Recombinant Human 52 kDa FK506 Binding Protein is produced by our E.coli expression system and the target gene encoding Met1-Ala459 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product FKBP4 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris,10 % glycerol, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
    Alternative Name
    FKBP4 (FKBP4 Products)
    Synonyms
    HBI Protein, p52 Protein, hsp56 Protein, PPIase Protein, fkbp52 Protein, fkbp59 Protein, MGC81078 Protein, wu:fb34f09 Protein, 59kDa Protein, AL022792 Protein, AW208983 Protein, FKBP-4 Protein, FKBP-52 Protein, FKBP52 Protein, FKPB52 Protein, p59 Protein, FKBP51 Protein, FKBP59 Protein, Hsp56 Protein, P59 Protein, FK506 binding protein 4 Protein, FK506 binding protein 4 S homeolog Protein, FKBP4 Protein, fkbp4.S Protein, fkbp4 Protein, Fkbp4 Protein
    Background

    Background: FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.

    Synonym: Peptidyl-prolyl cis-trans isomerase FKBP4, 51 kDa FK506-binding protein, 51 kDa FK506-binding protein, 59 kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP4

    Molecular Weight
    52.8 kDa
    UniProt
    Q02790
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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