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GPR114 Protein (Fc Tag)

GPR114 Origin: Human Host: HEK-293 Cells Recombinant > 94 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317740
  • Target See all GPR114 Proteins
    GPR114 (G Protein-Coupled Receptor 114 (GPR114))
    Protein Type
    Recombinant
    Origin
    • 5
    • 2
    Human
    Source
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GPR114 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human GPR114 Protein (Fc Tag)
    Sequence
    Met 1-Gly184
    Characteristics
    A DNA sequence encoding the human GPR114 (Q8IZF4) (Met1-Gly184) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 94 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GPR114 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    GPR114 (G Protein-Coupled Receptor 114 (GPR114))
    Alternative Name
    GPR114 (GPR114 Products)
    Synonyms
    PGR27 Protein, Gm1109 Protein, adhesion G protein-coupled receptor G5 Protein, ADGRG5 Protein, Adgrg5 Protein
    Background

    Background: GPR114 belongs to the G-protein coupled receptor 2 family. Members of this family share a common molecular architecture which consists of seven transmembrane domains, three extracellular loops, three intracellular loops, an amino-terminal extracellular domain and an intracellular carboxyl terminus. It is thought that light acts as the activating stimulus of a G-protein-coupled receptor (GPCR). GPCRs are expected to have molecular function (G-protein coupled receptor activity) and to localize in various compartments (endoplasmic reticulum membrane, plasma membrane, integral to membrane). Family B of the GPCRs is a small but structurally and functionally diverse group of proteins that includes receptors for polypeptide hormones, molecules thought to mediate intercellular interactions at the plasma membrane and a group of Drosophila proteins that regulate stress responses and longevity. GPR114 contains 1 GPS domain. GPR114 gene has been proposed to participate in processes (G-protein coupled receptor protein signaling pathway, neuropeptide signaling pathway).

    Synonym: GPR114,PGR27

    Molecular Weight
    45.6 kDa
    UniProt
    Q8IZF4
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