GOLM1 Protein (AA 40-401) (His tag)

Catalog No. ABIN7317315

Product Details

Target: GOLM1 (Golgi Membrane Protein 1 (GOLM1))

Protein Type: Recombinant

Protein Characteristics: AA 40-401

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This GOLM1 protein is labelled with His tag.

Purpose: Recombinant Human GOLPH2/GOLM1 Protein (aa 40-401, His Tag)

Sequence: Val 40-Leu 401

Characteristics: A DNA sequence encoding the human GOLM1 isoform 1 (Q8NBJ4-1) (Val 40-Leu 401) was fused with a polyhistidine tag at the C-terminus and a Met at the N-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: GOLM1 (Golgi Membrane Protein 1 (GOLM1))

Alternative Name: GOLPH2/GOLM1 (GOLM1 Products)

Synonyms: C9orf155 Protein, GOLPH2 Protein, GP73 Protein, PSEC0257 Protein, bA379P1.3 Protein, 2310001L02Rik Protein, AW125446 Protein, D030064E01Rik Protein, Golph2 Protein, GOLM1 Protein, golph2 Protein, gp73 Protein, golgi membrane protein 1 Protein, SPATA31 subfamily D, member 3 Protein, Golgi membrane protein 1 Protein, golgi membrane protein 1 L homeolog Protein, GOLM1 Protein, Golm1 Protein, Spata31d3 Protein, golm1 Protein, LOC100400549 Protein, golm1.L Protein

Background:

Background: Golgi membrane protein 1; also known as Golgi membrane protein GP73; Golgi phosphoprotein 2 and GOLM1; is a protein which belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in colon; prostate; trachea and stomach. It is expressed at lower level in testis; muscle; lymphoid tissues; white blood cells and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at low level in normal liver. Expression significantly increases in virus (HBV; HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease; autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH); GOLM1 is strongly expressed in hepatocyte-derived syncitial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.

Synonym: Golgi Membrane Protein 1; Golgi Membrane Protein GP73; Golgi Phosphoprotein 2; GOLM1; C9orf155; GOLPH2

Molecular Weight: 42.7 kDa