GRO gamma Protein (His tag)

Catalog No. ABIN7319995

Product Details

Target: GRO gamma (Growth Regulated Oncogene gamma (GRO gamma))

Protein Type: Recombinant

Origin: Mouse

Source: Yeast

Purification tag / Conjugate: This GRO gamma protein is labelled with His tag.

Purpose: Recombinant Mouse CXCL3/GRO gamma Protein (His Tag)

Sequence: Ala28-Ser100

Characteristics: A DNA sequence encoding the mouse Cxcl3 (NP_976065.1) (Ala28-Ser100) was expressed with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by SDS-PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, 50 % Glycerol, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: GRO gamma (Growth Regulated Oncogene gamma (GRO gamma))

Alternative Name: CXCL3/GRO gamma (GRO gamma Products)

Synonyms: CINC-2b Protein, GRO3 Protein, GROg Protein, MIP-2b Protein, MIP2B Protein, SCYB3 Protein, Cinc-2 Protein, Cinc2 Protein, Gm1960 Protein, Dcip1 Protein, C-X-C motif chemokine ligand 3 Protein, chemokine (C-X-C motif) ligand 3 Protein, CXCL3 Protein, Cxcl3 Protein

Background:

Background: CXCL3 is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3 autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. CXCL3 and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.

Synonym: Dcip1,Gm1960

Molecular Weight: 9.3 kDa

NCBI Accession: NP_976065