GMPR Protein (His tag)
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- Target See all GMPR Proteins
- GMPR (Guanosine Monophosphate Reductase (GMPR))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This GMPR protein is labelled with His tag.
- Purpose
- Recombinant Human GMPR Protein (Human Cells, His Tag)
- Sequence
- Met 1-Ser345
- Characteristics
- Recombinant Human GMP Reductase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Ser345 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GMPR Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl,40 % glycerol,0.15M NaCl and 1 mM DTT, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- GMPR (Guanosine Monophosphate Reductase (GMPR))
- Alternative Name
- GMPR (GMPR Products)
- Synonyms
- GMPR Protein, zgc:110617 Protein, GMPR1 Protein, 2310004P21Rik Protein, AV028449 Protein, Gmpr1 Protein, guanosine monophosphate reductase Protein, GMPR Protein, gmpr Protein, TP01_0363 Protein, Dd586_3518 Protein, Fbal_0005 Protein, Gmpr Protein
- Background
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Background: GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family. GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.
Synonym: GMP Reductase 1, Guanosine 5'-Monophosphate Oxidoreductase 1, Guanosine Monophosphate Reductase 1, GMPR, GMPR1
- Molecular Weight
- 38.5 kDa
- UniProt
- P36959
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