Histone H1 Protein (His tag)

Catalog No. ABIN7317720

Product Details

Target: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Histone H1 protein is labelled with His tag.

Purpose: Recombinant Human H1F0/Histone H1 Protein (His Tag)

Sequence: Met 1-Lys 194

Characteristics: A DNA sequence encoding the human H1F0 (P07305) (Met 1-Lys 194) was expressed, with a polyhistide tag at the N-terminus.

Purity: > 92 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 600 mM NaCl, 1 mM DTT, pH 8.5

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Alternative Name: H1F0/Histone H1 (H1F0 Products)

Synonyms: H5 Protein, h10 Protein, h1fv Protein, fb23b02 Protein, wu:fb23b02 Protein, zgc:65861 Protein, H1F0 Protein, H1fv Protein, H10 Protein, H1FV Protein, D130017D06Rik Protein, H1(0) Protein, h1(0)-1 Protein, h1f0 Protein, H1 Protein, H1 histone family member 0 Protein, H1 histone family, member 0 Protein, histone H1.0 Protein, H1 histone family member 0 S homeolog Protein, H1 histone family member 0 L homeolog Protein, histone I Protein, h1f0 Protein, H1F0 Protein, LOC698693 Protein, H1f0 Protein, h1f0.S Protein, h1f0.L Protein, his1 Protein

Background:

Background: H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-terminal and C-terminal tails. These tails are moderately conserved among species, but differ among variants, suggesting a specific function for each H1 variant. Studies on the role of particular subtypes at specific developmental stages in lower eukaryotes, but also in vertebrates suggest that specific subtypes of H1 participate in particular systems of gene regulation. 

Synonym: CPN60;GROEL;H10;H1FV;HLD4;HSP60;HSP65;HSPD1;HuCHA60;SPG13

Molecular Weight: 22.4 kDa

UniProt: P07305