HABP2 Protein (His tag)

Catalog No. ABIN7319410

Product Details

Target: HABP2 (Hyaluronan Binding Protein 2 (HABP2))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This HABP2 protein is labelled with His tag.

Purpose: Recombinant Human HABP2 Protein (His Tag)

Sequence: Met1-Gln279

Characteristics: Recombinant Human Hyaluronan-binding Protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Gln279 is expressed with a 6His tag at the C-terminus.

Purity: > 90 % as determined by SDS-PAGE

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: HABP2 (Hyaluronan Binding Protein 2 (HABP2))

Alternative Name: HABP2 (HABP2 Products)

Synonyms: HABP2 Protein, habp2 Protein, FSAP Protein, HABP Protein, HGFAL Protein, PHBP Protein, Fsap Protein, Habp Protein, Phbp Protein, AI035669 Protein, hyaluronan binding protein 2 Protein, hyaluronic acid binding protein 2 Protein, HABP2 Protein, habp2 Protein, Habp2 Protein

Background:

Background: Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.

Synonym: Hyaluronan-binding protein 2, Factor VII-activating protease, Factor seven-activating protease, Hepatocyte growth factor activator-like protein, Plasma hyaluronan-binding protein

Molecular Weight: 36.2 kDa

UniProt: Q14520