IGSF8 Protein (His tag)

Catalog No. ABIN7318613

Product Details

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This IGSF8 protein is labelled with His tag.

Purpose: Recombinant Human PGRL/IGSF8 Protein (His Tag)

Sequence: Arg28-Thr579

Characteristics: Recombinant Human Immunoglobulin Superfamily Member 8 is produced by our Mammalian expression system and the target gene encoding Arg28-Thr579 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Alternative Name: PGRL/IGSF8 (IGSF8 Products)

Synonyms: MGC77222 Protein, IGSF8 Protein, MGC151661 Protein, CD316 Protein, CD81P3 Protein, EWI-2 Protein, EWI2 Protein, KCT-4 Protein, LIR-D1 Protein, PGRL Protein, AA033172 Protein, AU041109 Protein, ESTM34 Protein, R75384 Protein, immunoglobulin superfamily, member 8 Protein, immunoglobulin superfamily member 8 Protein, igsf8 Protein, IGSF8 Protein, Igsf8 Protein

Background:

Background: Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.

Synonym: Immunoglobulin Superfamily Member 8, IgSF8, CD81 Partner 3, Glu-Trp-Ile EWI Motif-Containing Protein 2, EWI-2, Keratinocytes-Associated Transmembrane Protein 4, KCT-4, LIR-D1, Prostaglandin Regulatory-Like Protein, PGRL, CD316, IGSF8, CD81P3, EWI2, KCT4

Molecular Weight: 59.6 kDa

UniProt: Q969P0