IMPA1 Protein (His tag)
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- Target See all IMPA1 Proteins
- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IMPA1 protein is labelled with His tag.
- Purpose
- Recombinant Human IMP1/IMPA1 Protein (His Tag)
- Sequence
- Met 1-Asp277
- Characteristics
- Recombinant Human Inositol Monophosphatase 1 is produced by our E.coli expression system and the target gene encoding Met1-Asp277 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IMPA1 Protein
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Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) protein (His tag)
IMPA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) protein (GST tag)IMPA1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) protein (Strep Tag)Crystallography grade IMPA1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) protein (Strep Tag)Crystallography grade IMPA1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (Transcript Variant 2) protein (His tag)IMPA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)IMPA1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.25.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
- Alternative Name
- IMP1/IMPA1 (IMPA1 Products)
- Synonyms
- zgc:100926 Protein, 2610002K09Rik Protein, 2900059K10Rik Protein, AI325909 Protein, IMP Protein, IMPA Protein, impa Protein, inositol monophosphatase 1 Protein, inositol(myo)-1(or 4)-monophosphatase 1 Protein, inositol (myo)-1(or 4)-monophosphatase 1 Protein, inositol monophosphatase Protein, inositol(myo)-1(or 4)-monophosphatase 1 S homeolog Protein, impa1 Protein, Impa1 Protein, IMPA1 Protein, impa1.S Protein
- Background
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Background: Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family. IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.
Synonym: Inositol Monophosphatase 1, IMP 1, IMPase 1, Inositol-1(or 4)-Monophosphatase 1, Lithium-Sensitive Myo-Inositol Monophosphatase A1, IMPA1, IMPA
- Molecular Weight
- 32.3 kDa
- UniProt
- P29218
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