IMPA2 Protein (His tag)
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- Target See all IMPA2 Proteins
- IMPA2 (Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IMPA2 protein is labelled with His tag.
- Purpose
- Recombinant Human IMPA2/IMPase 2 Protein (His Tag)
- Sequence
- Met 1-Lys288
- Characteristics
- Recombinant Human Inositol Monophosphatase 2 is produced by our E.coli expression system and the target gene encoding Met1-Lys288 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IMPA2 Protein
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Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2) (AA 1-288) protein (His tag)
IMPA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2) (AA 1-288) protein (GST tag)IMPA2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2) (AA 1-288) protein (Strep Tag)Crystallography grade IMPA2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2) (AA 1-290) protein (Strep Tag)Crystallography grade IMPA2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2) protein (Myc-DYKDDDDK Tag)IMPA2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 2 mM DTT, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- IMPA2 (Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2))
- Alternative Name
- IMPA2/IMPase 2 (IMPA2 Products)
- Synonyms
- zgc:110201 Protein, 2210415D20Rik Protein, AI326924 Protein, AW259601 Protein, inositol monophosphatase 2 Protein, inositol(myo)-1(or 4)-monophosphatase 2 Protein, inositol (myo)-1(or 4)-monophosphatase 2 Protein, IMPA2 Protein, impa2 Protein, MGYG_08537 Protein, Impa2 Protein
- Background
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Background: Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.
Synonym: Inositol Monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-Monophosphatase 2, Myo-Inositol Monophosphatase A2, IMPA2, IMP.18P
- Molecular Weight
- 33.5 kDa
- UniProt
- O14732
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