ITLN1/Omentin Protein (His tag)

Catalog No. ABIN7318846

Product Details

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ITLN1/Omentin protein is labelled with His tag.

Purpose: Recombinant Human Intelectin-1/ITLN1 Protein (His Tag)

Sequence: Thr19-Ser298

Characteristics: Recombinant Human Intelectin-1 is produced by our E.coli expression system and the target gene encoding Thr19-Ser298 is expressed with a 6His tag at the N-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris,100 mMNaCl, 5 mM GSH, 0.5 mM GSSG, pH 8.0 .

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Alternative Name: Intelectin-1/ITLN1 (ITLN1 Products)

Synonyms: IntL Protein, Itln Protein, Itln2 Protein, Itln5 Protein, Itlna Protein, Lfr Protein, HL-1 Protein, HL1 Protein, INTL Protein, ITLN Protein, LFR Protein, hIntL Protein, omentin Protein, LfR Protein, Xeel Protein, hl-1 Protein, hl1 Protein, intl Protein, itln Protein, itln1 Protein, lfr Protein, xeel Protein, INTL1 Protein, zgc:153267 Protein, intelectin 1 (galactofuranose binding) Protein, intelectin 1 Protein, intelectin 1 L homeolog Protein, Itln1 Protein, ITLN1 Protein, itln1.L Protein, itln1 Protein

Background:

Background: Intelectin-1(ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDa Ca-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. The protein has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. It also may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosy l residues, in a calcium-dependent manner.

Synonym: Intelectin-1, ITLN-1, Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin, INTL, ITLN, LFR

Molecular Weight: 32.7 kDa

UniProt: Q8WWA0