IL1RAPL1 Protein (AA 19-357) (His tag)

Catalog No. ABIN7319571

Product Details

Target: IL1RAPL1 (Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1))

Protein Type: Recombinant

Protein Characteristics: AA 19-357

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This IL1RAPL1 protein is labelled with His tag.

Purpose: Recombinant Human IL-1R8/IL1RAPL1 Protein (aa 19-357, His Tag)

Sequence: Leu19-Thr357

Characteristics: Recombinant Human IL-1R8 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr357 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: IL1RAPL1 (Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1))

Alternative Name: IL-1R8/IL1RAPL1 (IL1RAPL1 Products)

Synonyms: Il1rapl Protein, 6330532G10Rik Protein, C030039N24 Protein, IL1R8 Protein, IL1RAPL Protein, MRX34 Protein, OPHN4 Protein, TIGIRR-2 Protein, MRX10 Protein, MRX21 Protein, wu:fi18g04 Protein, zgc:152866 Protein, interleukin 1 receptor accessory protein-like 1 Protein, interleukin 1 receptor accessory protein like 1 Protein, interleukin 1 receptor accessory protein-like 1a Protein, interleukin 1 receptor accessory protein-like 1b Protein, Il1rapl1 Protein, IL1RAPL1 Protein, il1rapl1a Protein, il1rapl1b Protein

Background:

Background: Interleukin-1 receptor accessory protein-like 1, also known as IL1RAPL1, can be detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. IL1RAPL1 functions as a homodimer, it interacts with NCS1, PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation, it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.

Synonym: Interleukin-1 Receptor Accessory Protein-Like 1, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, Oligophrenin-4, Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2, TIGIRR-2, X-Linked Interleukin-1 Receptor Accessory Protein-Like 1, IL1RAPL1, OPHN4

Molecular Weight: 40 kDa

UniProt: Q9NZN1

Pathways: Synaptic Membrane, Growth Factor Binding