IL1RAPL2 Protein (Fc Tag)

Catalog No. ABIN7196311

This Recombinant IL1RAPL2 protein is expressed in HEK-293 Cells.

Quick Overview for IL1RAPL2 Protein (Fc Tag) (ABIN7196311)

Target: IL1RAPL2 (Interleukin 1 Receptor Accessory Protein-Like 2 (IL1RAPL2))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Application: ELISA

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This IL1RAPL2 protein is labelled with Fc Tag.

Purpose: Recombinant Human IL-1R9/IL1RAPL2 Protein (Fc Tag)

Sequence: Met 1-Glu 356

Characteristics: A DNA sequence encoding the extracellular domain (Met 1-Glu 356) of human IL1R9 (NP_059112.1) precursor was expressed with the fused Fc region of human IgG1 at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Measured by its ability to bind biotinylated human IL1α in functional ELISA.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: IL1RAPL2 (Interleukin 1 Receptor Accessory Protein-Like 2 (IL1RAPL2))

Alternative Name: IL-1R9/IL1RAPL2

Background: IL1R,IL-1R,TIGIRR,IL1RAPL2,IL-1R9,IL1R9,IL1RAPL-2,TIGIRR-1,IL 1 RAPL 2,IL 1 receptor accessory protein like 2,IL 1R 9,IL 1R9,IL 1RAPL 2,IL1 receptor accessory protein like 2,IL-1 receptor accessory protein-like 2,IL-1R-9,IL1RAPL 2,IL-1RAPL-2,IL-1-RAPL-2,IL1RAPL2 related protein,IL1RAPL-2-related protein,Interleukin 1 receptor 9,Interleukin 1 receptor accessory protein like 2,Interleukin-1 receptor 9,IRPL2_HUMAN,Three immunoglobulin domain containing IL1 receptor related 1,Three immunoglobulin domain-containing IL-1 receptor-related 1,TIGIRR 1,TIGIRR1,X linked interleukin 1 receptor accessory protein like 2,X-linked interleukin-1 receptor accessory protein-like 2,X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9/IL1RAPL2 shows restricted expression in fetal brain and is highly homologous to IL1RAPL, which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptor are found in the fetal brain. IL-1R9/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci, and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.

Molecular Weight:

Calculated MW: 66.0 kDa

Observed MW: 80-85 kDa

Gene ID: 26280

NCBI Accession: NP_059112

UniProt: Q9NP60