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IL-11 Protein (Fc Tag)

This Recombinant IL-11 protein is produced in Human Cells.
Catalog No. ABIN7320821

Quick Overview for IL-11 Protein (Fc Tag) (ABIN7320821)

Target

See all IL-11 (IL11) Proteins
IL-11 (IL11) (Interleukin 11 (IL11))

Protein Type

Recombinant

Origin

  • 16
  • 9
  • 2
  • 2
Mouse

Source

  • 15
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This IL-11 protein is labelled with Fc Tag.

    Purpose

    Recombinant Mouse Interleukin-11/IL-11 Protein (Fc Tag)

    Sequence

    Pro22-Leu199

    Characteristics

    Recombinant Mouse Interleukin-11 is produced by our Mammalian expression system and the target gene encoding Pro22-Leu199 is expressed with a Fc tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    IL-11 (IL11) (Interleukin 11 (IL11))

    Alternative Name

    Interleukin-11/IL-11

    Background

    Background: Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.

    Synonym: Interleukin-11,Il11,IL-11

    Molecular Weight

    46.3 kDa

    UniProt

    P47873

    Pathways

    JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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