IZUMO1 Protein (His tag)
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- Target See all IZUMO1 Proteins
- IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IZUMO1 protein is labelled with His tag.
- Purpose
- Recombinant Human IZUMO1 Protein (His Tag)
- Sequence
- Met 1-Arg292
- Characteristics
- A DNA sequence encoding the human IZUMO1 (AAH34769.1) (Met1-Arg292) was expressed with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IZUMO1 Protein
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Izumo Sperm-Egg Fusion 1 (IZUMO1) (AA 51-211) protein (His tag)
IZUMO1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Izumo Sperm-Egg Fusion 1 (IZUMO1) (AA 22-292) protein (His tag)Crystallography grade IZUMO1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Izumo Sperm-Egg Fusion 1 (IZUMO1) (AA 22-319) protein (His tag)Crystallography grade IZUMO1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Izumo Sperm-Egg Fusion 1 (IZUMO1) (AA 22-350) protein (rho-1D4 tag)Crystallography grade IZUMO1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Izumo Sperm-Egg Fusion 1 (IZUMO1) (AA 22-397) protein (rho-1D4 tag)Crystallography grade IZUMO1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Izumo Sperm-Egg Fusion 1 (IZUMO1) protein (Myc-DYKDDDDK Tag)IZUMO1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))
- Alternative Name
- IZUMO1 (IZUMO1 Products)
- Synonyms
- IZUMO Protein, 1700058F15Rik Protein, Izumo Protein, izumo sperm-egg fusion 1 Protein, Ras interacting protein 1 Protein, IZUMO1 Protein, RASIP1 Protein, Izumo1 Protein
- Background
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Background: Izumo is a sperm membrane protein which plays a key role in the fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous sequences are known. Up to now, there four members has an N-terminal domain with significant homology to the N-terminal domain of Izumo. We call this domain Izumo domain. The four proteins are Izumo 1, 2, 3, and 4. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or the cytoplasmic domain or both of Izumo 1 are required for the formation of multimers of higher order. Izumo 1-3 are transmembrane proteins expressed specifically in the testis, and Izumo 4 is a soluble protein expressed in the testis and in other tissues. Izumo 1, 3, and 4 formed protein complexes on sperm, Izumo 1 forming several larger complexes and Izumo 3 and 4 forming a single larger complex. Izumo1 is essential for sperm-egg plasma membrane binding and fusion.
Synonym: IZUMO
- Molecular Weight
- 32.1 kDa
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