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KPNA2 Protein (His tag)

KPNA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318701
  • Target See all KPNA2 Proteins
    KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This KPNA2 protein is labelled with His tag.
    Purpose
    Recombinant Human KPNA2 Protein (His Tag)
    Sequence
    Met 1-Phe529
    Characteristics
    Recombinant Human Karyopherin Subunit alpha-2 is produced by our E.coli expression system and the target gene encoding Met1-Phe529 is expressed with a 6His tag at the N-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product KPNA2 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,1 mM DTT,20 % Glycerol, pH 8.0 .
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
    Alternative Name
    KPNA2 (KPNA2 Products)
    Synonyms
    IPOA1 Protein, QIP2 Protein, RCH1 Protein, SRP1alpha Protein, ima2 Protein, importin Protein, 2410044B12Rik Protein, PTAC58 Protein, Rch1 Protein, ipoa1 Protein, kpna2 Protein, qip2 Protein, rch1 Protein, srp1alpha Protein, hm:zeh0389 Protein, hm:zeh0389r Protein, zgc:113902 Protein, zgc:86945 Protein, karyopherin subunit alpha 2 Protein, importin subunit alpha-2 Protein, Importin subunit alpha-2 Protein, karyopherin (importin) alpha 2 Protein, karyopherin alpha-2 subunit like L homeolog Protein, karyopherin alpha 2 (RAG cohort 1, importin alpha 1) Protein, KPNA2 Protein, EDI_246290 Protein, EDI_335040 Protein, ima2 Protein, Kpna2 Protein, kpna2.L Protein, kpna2 Protein
    Background

    Background: Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.

    Synonym: Importin Subunit Alpha-2, Karyopherin Subunit Alpha-2, RAG Cohort Protein 1, SRP1-Alpha, KPNA2, RCH1, SRP1

    Molecular Weight
    60.0 kDa
    UniProt
    P52292
    Pathways
    M Phase, Protein targeting to Nucleus
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