LRRTM4 Protein (His tag)
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- Target See all LRRTM4 Proteins
- LRRTM4 (Leucine Rich Repeat Transmembrane Neuronal 4 (LRRTM4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LRRTM4 protein is labelled with His tag.
- Purpose
- Recombinant Human LRRTM4 Protein (His Tag)
- Sequence
- Met 1-Lys 424
- Characteristics
- A DNA sequence encoding the human LRRTM4 extracellular domain (NP_001128217.1) (Met 1-Lys 424) was expressed, fused with a polyhistidine tag at the C-terminus.
- Purity
- > 97 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LRRTM4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LRRTM4 (Leucine Rich Repeat Transmembrane Neuronal 4 (LRRTM4))
- Alternative Name
- LRRTM4 (LRRTM4 Products)
- Synonyms
- 7530419J18Rik Protein, A230052N11 Protein, RGD1560707 Protein, DKFZp459D155 Protein, leucine rich repeat transmembrane neuronal 4 Protein, LRRTM4 Protein, Lrrtm4 Protein, lrrtm4 Protein
- Background
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Background: Leucine-rich repeat transmembrane neuronal protein 4, also known as LRRTM4, is a single-pass type I membrane protein which belongs to the LRRTM family. LRRTM4 is expressed in the limb mesenchyme, neural tube, caudal mesoderm and in three distinct regions of the head. LRRTM4 may play a role in the development and maintenance of the vertebrate nervous system. Leucine-rich repeat containing proteins are involved in protein-protein interactions and they regulate numerous cellular events during nervous system development and disease. Human and mouse LRRTMs are highly conserved, and orthologous genes exist in other vertebrates but not in invertebrates. LRRTM mRNAs are predominantly expressed in the nervous system and that each LRRTM possesses a specific, partially nonoverlapping expression pattern. The structure and expression profile of LRRTM mRNAs suggest that they may have a role in the development and maintenance of the vertebrate nervous system. All LRRTMs, except LRRTM4, are located in the introns of different alpha-catenin genes, suggesting coevolution of these two gene families.
Synonym: UNQ3075/PRO9907;FLJ12568;MGC120633;MGC120636
- Molecular Weight
- 46.6 kDa
- NCBI Accession
- NP_001128217
- Pathways
- Synaptic Membrane
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