LMCD1 Protein (His tag)
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- Target See all LMCD1 Proteins
- LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LMCD1 protein is labelled with His tag.
- Purpose
- Recombinant Human LMCD1/Dyxin Protein (His Tag)
- Sequence
- Met 1-Ser365
- Characteristics
- Recombinant Human LIM and cysteine-rich domains protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Ser365 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LMCD1 Protein
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LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 1-365) protein (His tag)
LMCD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 1-365) protein (GST tag)LMCD1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 266-364) protein (GST tag)LMCD1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 1-365) protein (Strep Tag)Crystallography grade LMCD1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 1-365) protein (Strep Tag)Crystallography grade LMCD1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
LIM and Cysteine-Rich Domains 1 (LMCD1) protein (Myc-DYKDDDDK Tag)LMCD1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))
- Alternative Name
- LMCD1/Dyxin (LMCD1 Products)
- Synonyms
- LMCD1 Protein, AW455500 Protein, AW553074 Protein, dyxin Protein, LIM and cysteine rich domains 1 Protein, LIM and cysteine-rich domains 1 Protein, LMCD1 Protein, lmcd1 Protein, Lmcd1 Protein
- Background
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Background: LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Synonym: LIM and cysteine-rich domains protein 1, LMCD1, Dyxin
- Molecular Weight
- 44.0 kDa
- UniProt
- Q9NZU5
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