LSAMP Protein (His tag)

Catalog No. ABIN7317407

Product Details

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LSAMP protein is labelled with His tag.

Purpose: Recombinant Human LSAMP Protein (His Tag)

Sequence: Met 1-Asn 315

Characteristics: A DNA sequence encoding the human LSAMP (Q13449) (Met 1-Asn 315), without the pro peptide, was expressed, with a polyhistidine tag at the C-terminus.

Purity: > 97 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Alternative Name: LSAMP (LSAMP Products)

Synonyms: chLAMP Protein, IGLON3 Protein, LAMP Protein, 5430428I19 Protein, AW046674 Protein, B130007O04Rik Protein, D930023J12Rik Protein, Lam Protein, Lamp Protein, limbic system-associated membrane protein Protein, LSAMP Protein, Lsamp Protein

Background:

Background: The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system structures. The 64-68- kDa glycoprotein limbic system-associated membrane protein (LsAMP) is expressed on the surface of somata and proximal dendrites of neurons. These areas perform cognitive and autonomic functions, also learning and memory. The functional analysis indicates that LsAMP acts as a selective adhesion molecule, serving as a guidance cue for specific patterns of connectivity, which underlies the normal development of the limbic system. In animal studies there have been found that rats with increased level of anxiety had 1.6-fold higher expression of LsAMP gene in the periaqueductal gray compared to rats with low level of anxiety, indicating a possible role of LsAMP in the regulation of anxiety.

Synonym: FLJ34254,FLJ35396,FLJ37216,FLJ54658,IGLON3,LAMP

Molecular Weight: 33.4 kDa

UniProt: Q13449