MAN1B1 Protein (His tag)
-
- Target See all MAN1B1 Proteins
- MAN1B1 (Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This MAN1B1 protein is labelled with His tag.
- Purpose
- Recombinant Human MAN1B1 Protein (His Tag)
- Sequence
- Asp106-Ala699
- Characteristics
- Recombinant Human Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase/MAN1B1 is produced by our Mammalian expression system and the target gene encoding Asp106-Ala699 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MAN1B1 Protein
-
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 112-211) protein (GST tag)
MAN1B1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 106-699) protein (His tag)Crystallography grade MAN1B1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 72-658) protein (His tag)Crystallography grade MAN1B1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 1-699) protein (Strep Tag)Crystallography grade MAN1B1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) (AA 1-658) protein (Strep Tag)Crystallography grade MAN1B1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM TrisHCL,10 mM reduced Glutathione, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- MAN1B1 (Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))
- Alternative Name
- MAN1B1 (MAN1B1 Products)
- Synonyms
- erman1 Protein, mana-er Protein, MAN1B1 Protein, ERMAN1 Protein, MANA-ER Protein, MRT15 Protein, E430019H13Rik Protein, ERMan1 Protein, Gm108 Protein, RGD1563595 Protein, mannosidase alpha class 1B member 1 Protein, mannosidase, alpha, class 1B, member 1 L homeolog Protein, endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Protein, mannosidase, alpha, class 1B, member 1 Protein, MAN1B1 Protein, man1b1.L Protein, LOC480667 Protein, man1b1 Protein, Man1b1 Protein
- Background
-
Background: Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Synonym: Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase, ER Alpha-1,2-Mannosidase, ER Mannosidase 1, ERMan1, Man9GlcNAc2-Specific-Processing Alpha-Mannosidase, Mannosidase Alpha Class 1B Member 1, MAN1B1
- Molecular Weight
- 68.7 kDa
- UniProt
- Q9UKM7
-
