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MBIP Protein (His tag)

MBIP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318766
  • Target See all MBIP Proteins
    MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MBIP protein is labelled with His tag.
    Purpose
    Recombinant Human MBIP Protein (His Tag)
    Sequence
    Met 1-Pro344
    Characteristics
    Recombinant Human MAP3K12-Binding Inhibitory Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Pro344 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product MBIP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.0.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))
    Alternative Name
    MBIP (MBIP Products)
    Synonyms
    4933408E06Rik Protein, MAP3K12 binding inhibitory protein 1 Protein, Mbip Protein, mbip Protein, MBIP Protein
    Background

    Background: MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It's function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.

    Synonym: MAP3K12-Binding Inhibitory Protein 1, MAPK Upstream Kinase-Binding Inhibitory Protein, MUK-Binding Inhibitory Protein, MBIP

    Molecular Weight
    42.5 kDa
    UniProt
    Q9NS73
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