METTL1 Protein (His tag)
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- Target See all METTL1 Proteins
- METTL1 (Methyltransferase Like 1 (METTL1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This METTL1 protein is labelled with His tag.
- Purpose
- Recombinant Human METTL1 Protein (His Tag)
- Sequence
- Asp 32-Gln 265
- Characteristics
- A DNA sequence encoding the human METTL1 (NP_005362.3) (Asp 32-Gln 265) was expressed, with a polyhistide tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product METTL1 Protein
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Methyltransferase Like 1 (METTL1) (AA 1-276) protein (His tag)
METTL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Methyltransferase Like 1 (METTL1) (AA 1-276) protein (GST tag)METTL1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Methyltransferase Like 1 (METTL1) (AA 2-276) protein (His tag)Crystallography grade METTL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Methyltransferase Like 1 (METTL1) (AA 1-268) protein (Strep Tag)Crystallography grade METTL1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Methyltransferase Like 1 (METTL1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)METTL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, 0.5M NaCl, 20 % glycerol, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- METTL1 (Methyltransferase Like 1 (METTL1))
- Alternative Name
- METTL1 (METTL1 Products)
- Synonyms
- Dmel\\CG4045 Protein, EG:22E5.4 Protein, C12orf1 Protein, TRM8 Protein, TRMT8 Protein, YDL201w Protein, 2810012D02Rik Protein, CG4045 gene product from transcript CG4045-RA Protein, methyltransferase like 1 Protein, methyltransferase like 1 L homeolog Protein, tRNA (guanine46-N7)-methyltransferase Protein, tRNA (guanine-N(1)-)-methyltransferase Protein, tRNA (guanine-N7-)-methyltransferase Protein, CG4045 Protein, METTL1 Protein, Mettl1 Protein, mettl1.L Protein, CAALFM_C404810CA Protein, LOC100280508 Protein, LOC732983 Protein
- Background
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Background: tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein which belongs to the methyltransferase superfamily and TrmB family. METTL1 gene, has been identified by its sequence similarity to the yeast ORF YDL201w. The human cDNA and the genomic structure of METTL1 have been analyzed. The transcript contains 1292 nucleotides and codes for a protein of 276 amino acids. The METTL1 gene product shows high sequence similarities to putative proteins from mouse, Drosophila melanogaster, Arabidopsis thaliana, Caenorhabditis elegans, and yeast (39.8% identity between all six species). Computer analyses of the deduced protein sequence reveal two highly conserved amino acid motifs, one of which is typical for methyltransferases. Both motifs are also present in hypothetical proteins from eubacteria. Disruption of the homologous yeast ORF YDL201w shows that the gene is at least not essential for vegetative growth in Saccharomyces cerevisiae.
Synonym: C12orf1;TRM8;TRMT8;YDL201w
- Molecular Weight
- 28 kDa
- NCBI Accession
- NP_005362
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