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MECR Protein (His tag)

MECR Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319101
  • Target See all MECR Proteins
    MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This MECR protein is labelled with His tag.
    Purpose
    Recombinant Human MECR Protein (His Tag)
    Sequence
    Pro54-Met373
    Characteristics
    Recombinant Human Trans-2-Enoyl-CoA Reductase Mitochondrial is produced by our Mammalian expression system and the target gene encoding Pro54-Met373 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product MECR Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
    Alternative Name
    MECR (MECR Products)
    Synonyms
    CGI-63 Protein, FASN2B Protein, NRBF1 Protein, AI195831 Protein, Nrbf1 Protein, mitochondrial trans-2-enoyl-CoA reductase Protein, MECR Protein, Mecr Protein
    Background

    Background: Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lower levels in the placenta, liver, kidney and pancreas, with weakly or no expression in the lung. MECR exists as a homodimer, which catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. MECR may take part in the mitochondrial synthesis of fatty acids.

    Synonym: Trans-2-Enoyl-CoA Reductase Mitochondrial, Nuclear Receptor-Binding Factor 1, HsNrbf-1NRBF-1, MECR, NBRF1

    Molecular Weight
    35.7 kDa
    UniProt
    Q9BV79
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