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MEGF10 Protein (His tag)

MEGF10 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317160
  • Target See all MEGF10 Proteins
    MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))
    Protein Type
    Recombinant
    Origin
    • 3
    • 3
    Human
    Source
    • 6
    HEK-293 Cells
    Purification tag / Conjugate
    This MEGF10 protein is labelled with His tag.
    Purpose
    Recombinant Human MEGF10 Protein (His Tag)
    Sequence
    Met 1-Gly857
    Characteristics
    A DNA sequence encoding the human MEGF10 (NP_115822.1) (Met1-Gly857) was expressed with a polyhistidine tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product MEGF10 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))
    Alternative Name
    MEGF10 (MEGF10 Products)
    Synonyms
    EMARDD Protein, 3000002B06Rik Protein, Gm331 Protein, multiple EGF-like domains 10 Protein, multiple EGF like domains 10 Protein, multiple EGF-like-domains 10 Protein, Megf10 Protein, MEGF10 Protein
    Background

    Background: This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.

    Synonym: EMARDD

    Molecular Weight
    90.2 kDa
    NCBI Accession
    NP_115822
    Pathways
    Regulation of Muscle Cell Differentiation
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